How "Flying Death" Has Saved Hundreds of Lives

  • Added:  9 days ago
  • Curare, known as "flying death," was used for centuries to make poisoned arrows. Scientists discovered how to use it to create life saving medical treatments that we still use today.

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    Sources:

    http://onlinelibrary.wiley.com/doi/10.1038/sj.bjp.0706404/abstract
    http://www.sciencedirect.com/topics/page/Curare
    http://www.
    sciencedirect.com/science/article/pii/B9780123864543004826
    http://www.med.uottawa.ca/historyofmedicine/hetenyi/milner.html
    http://nickalls.org/dick/papers/anes/curare1985a.pdf
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2312021/
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1279945/
    http://neuroscience.uth.tmc.edu/s1/chapter04.html
    https://books.google.com/books?id=_Du2bfrO9FwC&pg=PA527
    https://www.atsdr.cdc.gov/toxprofiles/tp6.pdf
    https://www.atsdr.cdc.gov/phs/phs.asp?id=51&tid=16
  • Video CategoriesEducation
  • Runtime: 4:31
  • Tags for this video:  SciShow  science  Hank  Green  education  learn  poison  darts  arrows  curare  flying death  skeletal muscles  Chondrodendron tomentosum  tubocurarine  alkaloid  neuromuscular blocking agent  anesthesia  chloroform  strychnos toxifera  

Comments: 464

  • R.B.
    R.B. 4 days ago

    Why is there flying death around my anus?

  • Trish Brock
    Trish Brock 5 days ago

    Is this also related to any of the drugs they use today for "seizure" medications? Or medications to stop "ticking" movements in many people that have disabilities or that may experience from side effects from other medications? Just curious...thank you.

  • AnthonyMazzarella
    AnthonyMazzarella 5 days ago

    Curaure is not a poison it is a venom. poison is toxic when ingested, venom when injected.

  • Milius. Genghis Khan. 2017

    Time to save hundreds of people by donning warpaint, beating my chest and screaming at the top of my lungs in the jungles of 'nam.

  • Sophie the Jedi Knight

    Fun fact: curare is Latin for "to cure"

  • neverAskMeWhy07
    neverAskMeWhy07 7 days ago

    1:05 "back breaking convulsions during shock therapy" let that sink in...

  • doudy126
    doudy126 7 days ago

    How can you catch helicobacter Pylori ?

  • Laura K
    Laura K 7 days ago

    Science and history in one video? Must be my lucky day! Thanks SciShow!

  • Vasilis Tsitsos
    Vasilis Tsitsos 7 days ago

    Hey! This guy doesnt look like a nerd!!!

  • FluteGeek09
    FluteGeek09 8 days ago

    MONTREAL!!!! YAS, Canada!

  • moreCuriousThanACat

    what's sad is that destruction of rainforests across the world have possibly wiped out some potential scientific advancements provided by nature

  • Fredrik Åfeldt
    Fredrik Åfeldt 8 days ago

    "Generally, anesthesia is a way to make people..."
    Pun intended? As in "genereal anesthesia"? I see what you may or may not have done there.

  • coletteitsfrench
    coletteitsfrench 8 days ago

    Same research was also used to create the first treatment for Myasthenia gravis. The antidote for curare is an acetylcholinesterase inhibitor and a british doctor recognized that that would help her patient that had similar symptoms as someone with curare poisoning.

  • maattthhhh
    maattthhhh 8 days ago

    so... some anesthesia can paralyze the lungs, but not the heart?

  • Andre Tsang
    Andre Tsang 8 days ago

    "Generally, anesthesia"

    ayy

  • Manthan Shah
    Manthan Shah 8 days ago

    anyone learned about curare from tintin?

  • Christopher Day
    Christopher Day 8 days ago

    So can tubocurarine be used as a treatment for Sarin poisoning?

  • john doe
    john doe 8 days ago

    Kind of the opposite of an acetylcholine esterase inhibitor like sarin?

  • Ryan Frank
    Ryan Frank 8 days ago

    i like your haircut :)

  • Brigantos Orcaitori

    Poisons are ingested
    Venums are injected

  • ERROR
    ERROR 8 days ago

    during some part earlier in my life, I developed spasming, but only (sometimes) when I yawn or stretch after a while.

  • ERROR
    ERROR 8 days ago

    I don't think we'll be making medicine that includes parts of manchineel trees. ever.

  • Pre Example
    Pre Example 8 days ago

    THE POISON ARROWS IN ORANGE IS THE NEW BLACK SAVED THE INMATES LIVES

  • Russkiy Smiffy
    Russkiy Smiffy 8 days ago

    @0:56 dat donkey was given some LSD too?

  • Natanel Sharabi
    Natanel Sharabi 8 days ago

    _Cave Johnson here. we thank you for your contribution. TO SCIENCE!_

  • dino boss
    dino boss 8 days ago

    is soda really caffeine free?

  • Sean Walaszek
    Sean Walaszek 8 days ago

    thats dat Michael Jackson juice...

  • Afrika Smith
    Afrika Smith 8 days ago

    I bet this made alot of injured WWll soilders happy.

  • Zachary Moore
    Zachary Moore 8 days ago

    No snakes are poisonous... 1:20

  • finder3
    finder3 8 days ago

    how is this on trending with 200k views

  • anonymous
    anonymous 8 days ago

    complete BS that you can eat a poison arrow frog's poison and it will "do nothing" it's 3000x more potent than morphine which is why the horse had to be put on a ventilator,it can be destroyed by the digestive system but so is morphine which gives it 10% bolavailability,but under the tongue or applied to mucous membranes you're doing to die

  • Manny Owlstein
    Manny Owlstein 8 days ago

    Did they at least get to eat the donkeys?

  • Leopoldo Aranha
    Leopoldo Aranha 9 days ago

    Shouldn't royalties be paid for those native tribes? *nudges the big pharma*

  • carson smith
    carson smith 9 days ago

    I knew this because of skyrim when Karliah shot you with a poison that paralyzes you and slows your heart rate preventing blood loss

  • Kevin Turtles
    Kevin Turtles 9 days ago

    Rip shrek's donkey and donkeys baby dragon donkey's

  • Korvin Ezüst
    Korvin Ezüst 9 days ago

    How else thought of Deadshot immediately when Michael said "curare"?

  • Petros Adamopoulos
    Petros Adamopoulos 9 days ago

    Worries for a couple of donkeys after mentioning people have been using the thing on animals for millennia to kill them. Insults my intelligence.

  • topper007style
    topper007style 9 days ago

    Really enjoyed this one. Reminded me a lot of the James Burke series 'Connections'--would love to see more stuff like this!

  • MrCarter'sRods
    MrCarter'sRods 9 days ago

    You guys should explain why it hurts when people pee.

  • Tactical Idiots
    Tactical Idiots 9 days ago

    Wouldn't that make it a venom?

  • IntroWellness
    IntroWellness 9 days ago

    Each batch was a gamble 🙈

  • Bob Sweet
    Bob Sweet 9 days ago

    Super impressed you just said "Montreal" 👍 Americans usually say the city then the country for some reason; like you wouldn't know where Manchester or Perth is lol

  • Tihowiel
    Tihowiel 9 days ago

    just imagined a superhero shooting arrows with medicine. "Oh i think i have a col..." BOOM HEADSHOT

  • Fraser Henderson
    Fraser Henderson 9 days ago

    "screws with the chemical messages". This techno-speak is so hard to understand, could you dumb it down a bit for us small brained viewers?

  • I dont know what to put for my username

    The only reason why I know what "curare" is, is because of arrow...

  • vichetca
    vichetca 9 days ago

    Bless those 2 donkeys

  • OverKnight 52
    OverKnight 52 9 days ago

    This is legit? It was on arrow, deadshot would lace his bullets with this poison and if the. Bullet didnt kill you the poison would in about 5 minutes

  • spongekupo
    spongekupo 9 days ago

    ah shot of curare

  • Warrior Son
    Warrior Son 9 days ago

    Donkey died
    Daddy cried
    Inky pinky ponky....
    😔

    • Meg Ravenclaw
      Meg Ravenclaw 8 days ago

      Inky binky bonky
      Daddy had a donkey
      Donkey died
      Daddy cried
      Inky binky bonky

      Inky binky bonky
      Daddy had a donkey
      Daddy died
      Donkey cried
      Inky binky bonky


  • Benjamin Hershey
    Benjamin Hershey 9 days ago

    So they just jabbed needles and injected poison into the donkeys? Sounds like a real pain in the ass!

  • Shak Pherze
    Shak Pherze 9 days ago

    I was pierced by an arrow once. Since then I've been having hallucinations of an imaginary friend who can punch things

  • Max Mick
    Max Mick 9 days ago

    I have a suggestion for the next video! "Why does my CRT make that high-pitched noise?"

  • Xir's Royal Majesty Oliver Cromwell

    not a poison

  • Margarita Zaboloteny

    he got buff

  • 2Awesome
    2Awesome 9 days ago

    How did the donkey #3 not fall over? Can it stand up with muscles not working?

  • Harry PAnnU !
    Harry PAnnU ! 9 days ago

    mate u gained bit weight lately

  • huldu
    huldu 9 days ago

    I love when men poke around inside my body, especially black men. They can touch areas no others can reach.

  • Telleryn
    Telleryn 9 days ago

    Another reason to protect what natural biodiversity we have left in rainforest and reef, who knows what other potentially useful molecules are out there

  • sifat md abdullah
    sifat md abdullah 9 days ago

    did the guy get fat? :/

  • Shall NotWither
    Shall NotWither 9 days ago

    Thumbs up mention of Ecuador.

  • Terrell Perry
    Terrell Perry 9 days ago

    stealing Europeans what's new

  • Asd Fg
    Asd Fg 9 days ago

    Are you starting to put on some weigh there mate?

  • KiddsockTV
    KiddsockTV 9 days ago

    I Love the technical term of "screws"

  • Gothead420
    Gothead420 9 days ago

    Plants are plain amazing.
    What a biochemical wealth to explore...

  • Gexxys
    Gexxys 9 days ago

    It isn't dangerous when eating it?
    Eats Curare to prove it isn't dangerous, accidently bites his tongue, dies from poison

  • Robbie Keith
    Robbie Keith 9 days ago

    Your hair looks good in this video.

  • denis pucheu
    denis pucheu 9 days ago

    They were using an anesthetic extracted from a Murex thousands of years ago. Pliny wrote about it.

  • infirmux
    infirmux 9 days ago

    So the 3rd donkey was killed promptly after they ate the first two?

  • Gin the raptor
    Gin the raptor 9 days ago

    What can electricity do to the human body as a weapon?

  • MineFish [DP]
    MineFish [DP] 9 days ago

    0:55 that donkey is me.

  • psycho Professor
    psycho Professor 9 days ago

    use haoushoku haki.... unconscious in a sec..

  • Lala Bb
    Lala Bb 9 days ago

    Why are there poison arrows around my anus?

  • DolanPls
    DolanPls 9 days ago

    "Thats how they did science back in the day" That's still how we do science today to be fair

  • Lightning Bug
    Lightning Bug 9 days ago

    it's nice to know how anesthesia was invented. I am still wondering how suppositories were invented! I suppose some scientist said one day: "where should we put this medicine? oh! I know, let's put it in 3rd donkey's butt while he's still under anesthesia!"

  • miloradvlaovic
    miloradvlaovic 9 days ago

    Someone's gotten a bit ... on the chubby side o.O

  • Dragnerve
    Dragnerve 9 days ago

    I once was saved from bleeding to death cuz my friend Karliah used a poisoned arrow on me before I got stabbed by Mercer.

  • Frank Winterlong
    Frank Winterlong 9 days ago

    Q'rahre? xD

  • Fruiplusel - Crunchy Rainbow

    can you tell what actually happen if put vga into water when connecting computer ??

    • Fruiplusel - Crunchy Rainbow
      Fruiplusel - Crunchy Rainbow 9 days ago

      NeeoAnt but if put salt and copper ??


    • NeeoAnt
      NeeoAnt 9 days ago

      VGA is a graphics standard, an immaterial thing, and as such you can't put it into water.

      If mean something else, then it would get wet, obviously.


  • James Cashman
    James Cashman 9 days ago

    I used to be a Scientists like you, but then I took a poison arrow to the knee...

  • zeinul
    zeinul 9 days ago

    Hey man, you're getting fatter. Check your calories.

  • TheGoggles
    TheGoggles 9 days ago

    Science hates donkeys!

  • rillloudmother
    rillloudmother 9 days ago

    Only Hundreds of lives? Am I missing something?

  • Luke Paul
    Luke Paul 9 days ago

    love the donkey.

  • Storm Talifero
    Storm Talifero 9 days ago

    by the way you described it CURARE is a venom not poison it drives me crazy when people mix these up so stop saying poison

  • My main is Kid Cobra go away Min Min

    Why do I produce more snot when I cry?

    • My main is Kid Cobra go away Min Min
      My main is Kid Cobra go away Min Min 8 days ago

      Wow. I did not know that.


    • Meghan Darrah
      Meghan Darrah 9 days ago

      it's based entirely on the placement and the flow of movement through the tear ducts. tears begin in a duct that sits along the outer side of the upper eyelid, and along with tear production, there are two more ducts in the inner corner of the eye and along the nasal passage. the filtration of tears and clearing of the eye follows a path from the top, outer corner of the eye, across the eye, over to the inner corner of the eye, and down the nasal passage. excess fluid that is cleared away by the tear ducts in congruence with the tears that leave the eye due to overflow will drain into the nasal passages, causing the oh so familiar runny nose.


  • Ibro N
    Ibro N 9 days ago

    How does ripping up the lungs and stuffing an air tube into it going to work?

  • Robert Szasz
    Robert Szasz 9 days ago

    ROC rocks
    SUX sucks. 😉

  • Christopher Ellis
    Christopher Ellis 9 days ago

    sixteenth, and nineteenth, century, if you please. People from all over the world watch this, so try using standard English, rather than parochial terms. anæsthesia!
    poison in small doses can cure, but many small doses can accumulate, resulting in illness and death, like alcohol or tobacco.

  • The Angry Korean
    The Angry Korean 9 days ago

    well that's the first time a couple of Jackasses saved millions of people.

  • trash juice
    trash juice 9 days ago

    Michael Aranda is adorable

  • Mihai Mihai
    Mihai Mihai 9 days ago

    curare is not an anesthetic , it just paralyze.

  • Crystal_ignition
    Crystal_ignition 9 days ago

    interesting!

  • ArkbladeIX
    ArkbladeIX 9 days ago

    I have a poison tip

  • Unicorn Fluff Puff
    Unicorn Fluff Puff 9 days ago

    Gory sciences please!!!!!! Like history OF scalpel ... thanks! 🙂🙂

  • Michael S
    Michael S 9 days ago

    yo, anyone else notice his eyes. reminds me of me back when I had to use steriods on mine

  • Andreas Björkman
    Andreas Björkman 9 days ago

    If it has to get into the bloodstream it's not a poison, it's a venom. smh

  • Dany Siegh
    Dany Siegh 9 days ago

    So the flying death helped people live? That is ironic.

  • Marcel Eckhard
    Marcel Eckhard 9 days ago

    We had Curare in our advanced Biology curs :P

  • Jr de Barbosa
    Jr de Barbosa 9 days ago

    Serendipity...damn writers. lol..

  • 125687edu
    125687edu 9 days ago

    if it has to get into the bloodstream its not poisenos than it is venomos I am sirry for my english I am dutch

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